YWHAB / 14-3-3 Beta Antibody

APR13974G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR13974G		50 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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YWHAB / 14-3-3 Beta Antibody

品牌	Leading Biology	貨號	APR13974G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality YWHAB / 14-3-3 Beta antibody.
分子量	28kDa
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
宿主	Rabbit
種屬反應(yīng)性	Human, Zebrafish
靶點	Human 14-3-3 beta. Predicted cross-reactivity based on amino acid sequence homology: mouse (84%), rat (97%), zebrafish (82%).
基因ID	7529
UniProt ID	P31946
功能	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.
總結(jié)	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.
形式	Liquid. In PBS containing 0.02% sodium azide.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF, ICC
稀釋方法	IF (1:100-1:200), IHC-P (5 μg/ml), WB (1:5000-1:20000)
別名	14-3-3 protein beta/alpha, Protein 1054, Protein kinase C inhibitor protein 1, KCIP-1, 14-3-3 protein beta/alpha, N-terminally processed, YWHAB
圖像	Immunofluorescence of paraformaldehyde-fixed HeLa, using 14-3-3 beta antibody at 1:200 dilution. Sample (30 ug of whole cell lysate). A: Raji. 12% SDS PAGE. YWHAB antibody diluted at 1:10000. Anti-14-3-3 Beta antibody IHC of human cerebellum.
說明書	Product Datasheet Protocol
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