NR1H3 / LXR Alpha Antibody (N-Terminus)

APR08816G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR08816G		50 μg / ￥4950

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NR1H3 / LXR Alpha Antibody (N-Terminus)

品牌	Leading Biology	貨號	APR08816G
產(chǎn)品分類	Polyclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NR1H3 / LXR Alpha antibody (N-Terminus).
分子量	50kDa
細胞定位	Antigen Cellular Localization: Nucleus {ECO:0000255\|PROSITE- ProRule:PRU00407}
宿主	Rabbit
種屬反應性	Human, Mouse, Rat
靶點	Human NR1H3
通用名	LXRA
基因ID	10062
UniProt ID	Q13133
功能	Nuclear receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand- binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half- sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity).
總結	Nuclear receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand- binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half- sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity).
形式	Liquid
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, IHC-P, IF, E
稀釋方法	IHC-P (5 μg/ml), WB (1-2 μg/ml),
別名	Oxysterols receptor LXR-alpha, Liver X receptor alpha, Nuclear receptor subfamily 1 group H member 3, NR1H3, LXRA
圖像	Immunofluorescence of LXR-A in rat liver tissue with LXR-A antibody at 20 ug/ml. Western blot of LXR-A in rat liver tissue lysate with LXR-A antibody at (A) 1 and (B) 2 ug/ml. Anti-NR1H3 / LXR Alpha antibody IHC of human small intestine.
說明書	Product Datasheet Protocol
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