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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > FMR1 / FMRP Antibody

FMR1 / FMRP Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM05877G 50 μg / ¥4950

FMR1 / FMRP Antibody

品牌

Leading Biology

貨號(hào)

AMM05877G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FMR1 / FMRP antibody.

分子量

71kDa

細(xì)胞定位

Antigen Cellular Localization: Cytoplasm. Nucleus, nucleolus.

宿主

Goat

種屬反應(yīng)性

Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Dog

靶點(diǎn)

Human FMR1.

基因ID

UniProt ID

功能

Translation repressor. Component of the CYFIP1-EIF4E- FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA- binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).

總結(jié)

Translation repressor. Component of the CYFIP1-EIF4E- FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA- binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).

形式

Liquid

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, E

稀釋方法

ELISA (1:32000), IHC-P (2.5 μg/ml), WB (0.3-1 μg/ml)

別名

Fragile X mental retardation protein 1, FMRP, Protein FMR-1, FMR1

圖像

Antibody (0.3 ug/ml) staining of HeLa lysate (35 ug protein in RIPA buffer).

Anti-FMR1 antibody IHC of human placenta.

說(shuō)明書

數(shù)量

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