CFLAR / FLIP Antibody (aa191-209)

APG02537G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APG02537G		50 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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CFLAR / FLIP Antibody (aa191-209)

品牌	Leading Biology	貨號(hào)	APG02537G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CFLAR / FLIP antibody (aa191-209).
分子量	55kDa
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
靶點(diǎn)	FLIP antibody was raised against a peptide corresponding to amino acids 191 to 209 at C-terminus of human FLIP form2.
通用名	CASH, CASP8AP1, CLARP, MRIT
基因ID	8837
UniProt ID	O15519
功能	Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
總結(jié)	Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF, ICC, E
稀釋方法	IHC-P (5 μg/ml), WB (1:1000),
別名	CASP8 and FADD-like apoptosis regulator, Caspase homolog, CASH, Caspase-eight-related protein, Casper, Caspase-like apoptosis regulatory protein, CLARP, Cellular FLICE-like inhibitory protein, c-FLIP, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, I-FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, CASP8 and FADD-like apoptosis regulator subunit p43, CASP8 and FADD-like apoptosis regulator subunit p12, CFLAR, CASH, CASP8AP1, CLARP, MRIT
圖像	Immunofluorescence of FLIP in HeLa cells with FLIP antibody at 10 ug/ml. Anti-CFLAR / FLIP antibody IHC of human lung. Anti-CFLAR / FLIP antibody IHC of human pancreas.
說(shuō)明書	Product Datasheet Protocol
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