APG4B / ATG4B Antibody

APG01912G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APG01912G		50 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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APG4B / ATG4B Antibody

品牌	Leading Biology	貨號(hào)	APG01912G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality APG4B / ATG4B antibody.
分子量	44kDa
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm.
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat, Zebrafish, Chicken, Xenopus
靶點(diǎn)	A portion of amino acid 350-400 of human APG4B
通用名	APG4B, AUTL1, KIAA0943
基因ID	23192
UniProt ID	Q9Y4P1
功能	Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C- terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
總結(jié)	Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C- terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P
稀釋方法	IHC-P (10 μg/ml), WB (1-3 μg/ml),
別名	Cysteine protease ATG4B, 3.4.22.-, AUT-like 1 cysteine endopeptidase, Autophagin-1, Autophagy-related cysteine endopeptidase 1, Autophagy-related protein 4 homolog B, hAPG4B, ATG4B, APG4B, AUTL1, KIAA0943
圖像	Western blot of APG4B in HeLa cell lysate in the 1) absence, and 2) presence of immunizing... Anti-ATG4B antibody IHC of human heart.
說(shuō)明書(shū)	Product Datasheet Protocol
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