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Polyclonal Antibodies >
PTPN11 / SHP-2 / NS1 Antibody (N-Terminus)品牌 |
Leading Biology | 貨號(hào) |
APR13012G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PTPN11 / SHP-2 / NS1 antibody (N-Terminus).
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分子量 |
68kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
14 amino acid peptide from near the amino terminus of human SHP2
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通用名 |
PTP2C, SHPTP2
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基因ID |
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UniProt ID |
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功能 |
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.
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總結(jié) |
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF
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稀釋方法 |
IHC-P (5 μg/ml)
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別名 |
Tyrosine-protein phosphatase non-receptor type 11, 3.1.3.48, Protein-tyrosine phosphatase 1D, PTP-1D, Protein-tyrosine phosphatase 2C, PTP-2C, SH-PTP2, SHP-2, Shp2, SH-PTP3, PTPN11, PTP2C, SHPTP2
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圖像 |
Western blot of SHP2 in mouse skeletal muscle tissue lysate with SHP2 antibody at (A) 0.5 and... Immunofluorescence of SHP2 in Human Skeletal Muscle cells with SHP2 antibody at 20 ug/ml. Anti-PTPN11 antibody IHC of human brain, cortex. |
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說(shuō)明書(shū) |
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數(shù)量 |
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