CRFR1 / CRHR1 Antibody (N-Terminus)

APG02763G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APG02763G		50 μg / ￥4950

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CRFR1 / CRHR1 Antibody (N-Terminus)

品牌	Leading Biology	貨號(hào)	APG02763G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CRFR1 / CRHR1 antibody (N-Terminus).
分子量	51kDa
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein. Endosome. Note=Agonist-binding promotes endocytosis
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Hamster, Monkey
靶點(diǎn)	Human CRF1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
通用名	CRFR, CRFR1, CRHR
基因ID	1394
UniProt ID	P34998
功能	G-protein coupled receptor for CRH (corticotropin- releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
總結(jié)	G-protein coupled receptor for CRH (corticotropin- releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	IHC-P
稀釋方法	IHC-P (1-2 μg/ml)
別名	Corticotropin-releasing factor receptor 1, CRF-R-1, CRF-R1, CRFR-1, Corticotropin-releasing hormone receptor 1, CRH-R-1, CRH-R1, CRHR1, CRFR, CRFR1, CRHR
圖像	Anti-CRFR1 / CRHR1 antibody IHC of human brain, amygdala. Anti-CRF1 antibody APG02763G IHC of human pituitary. Anti-CRFR1 / CRHR1 antibody IHC of human Skin, Melanoma.
說(shuō)明書(shū)	Product Datasheet Protocol
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