MRGPRX2 / MRGX2 Antibody (Extracellular Domain)

AMM06479G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM06479G		50 μg / ￥4950

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MRGPRX2 / MRGX2 Antibody (Extracellular Domain)

品牌	Leading Biology	貨號(hào)	AMM06479G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MRGPRX2 / MRGX2 antibody (Extracellular Domain).
分子量	37kDa
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein.
宿主	Rabbit
種屬反應(yīng)性	Human, Monkey
靶點(diǎn)	Human MRGPRX2 / MRGX2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MRGPRX1 (71%), MRGPRX4 (64%), MRGPRX3 (57%).
通用名	MRGX2
基因ID	117194
UniProt ID	Q96LB1
功能	Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin- stimulated cAMP levels, suggesting that this receptor is G(q)- coupled.
總結(jié)	Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin- stimulated cAMP levels, suggesting that this receptor is G(q)- coupled.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	IHC-P
稀釋方法	IHC-P (2-4 μg/ml)
別名	Mas-related G-protein coupled receptor member X2, MRGPRX2, MRGX2
圖像	Anti-MRGPRX2 / MRGX2 antibody IHC of human Skin, Melanoma. Anti-MRGPRX2 / MRGX2 antibody IHC of human Lung, Non-Small Cell Carcinoma.
說(shuō)明書	Product Datasheet Protocol
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MRGPRX2 / MRGX2 Antibody (Extracellular Domain)