全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM06463G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MRGD / MRGPRD antibody (Cytoplasmic Domain).
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分子量 |
36kDa
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein Note=Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine
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宿主 |
Rabbit
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種屬反應性 |
Human, Monkey
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靶點 |
Human MRGPRD. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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通用名 |
MRGD
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基因ID |
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UniProt ID |
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功能 |
May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin- stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).
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總結(jié) |
May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin- stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
IHC-P
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稀釋方法 |
IHC-P (17 μg/ml)
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別名 |
Mas-related G-protein coupled receptor member D, Beta-alanine receptor, G-protein coupled receptor TGR7, MRGPRD, MRGD
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圖像 |
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說明書 |
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數(shù)量 |
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