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> 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > MRGX1 / MRGPRX1 Antibody (N-Terminus)品牌 |
Leading Biology | 貨號(hào) |
AMM06487G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MRGX1 / MRGPRX1 antibody (N-Terminus).
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分子量 |
36kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Monkey
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靶點(diǎn) |
Human MRGPRX1 / MRGX1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MRGPRX3 (71%).
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通用名 |
MRGX1, SNSR3, SNSR4
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基因ID |
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UniProt ID |
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功能 |
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine- induced itch, in a histamine-independent manner.
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總結(jié) |
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine- induced itch, in a histamine-independent manner.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC-P, ICC
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稀釋方法 |
IHC-P (12 μg/ml)
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別名 |
Mas-related G-protein coupled receptor member X1, Sensory neuron-specific G-protein coupled receptor 3/4, MRGPRX1, MRGX1, SNSR3, SNSR4
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圖像 |
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說明書 |
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數(shù)量 |
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