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SMO / Smoothened Antibody (1st Extracellular Domain)品牌 |
Leading Biology | 貨號(hào) |
APR13406G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SMO / Smoothened antibody (1st Extracellular Domain).
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分子量 |
86kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein. Cell projection, cilium
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
Human SMO. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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通用名 |
SMOH
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基因ID |
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UniProt ID |
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功能 |
G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
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總結(jié) |
G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC-P
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稀釋方法 |
IHC-P (1:400)
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別名 |
Smoothened homolog, SMO, Protein Gx, SMO, SMOH
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圖像 |
Human, Testis: Formalin-Fixed Paraffin-Embedded (FFPE) Anti-SMO / Smoothened antibody IHC of human Ovary, Carcinoma. Anti-SMO / Smoothened antibody IHC of human brain, cortex. |
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說明書 |
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數(shù)量 |
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