品牌 |
Leading Biology |
貨號 |
APR12254G |
產品分類 |
Polyclonal Antibodies |
研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GPRC6A antibody (N-Terminus).
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分子量 |
105kDa
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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種屬反應性 |
Human
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靶點 |
Human GPRC6A. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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基因ID |
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UniProt ID |
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功能 |
Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+). Activated by extracellular calcium and osteocalin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinates nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalents ions and its responsiveness to anabolic steroids.
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總結 |
Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+). Activated by extracellular calcium and osteocalin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinates nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalents ions and its responsiveness to anabolic steroids.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
IHC-P
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稀釋方法 |
IHC-P (5 μg/ml)
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別名 |
G-protein coupled receptor family C group 6 member A, hGPRC6A, G-protein coupled receptor GPCR33, hGPCR33, GPRC6A
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圖像 |
Anti-GPRC6A antibody APR12254G IHC of human lung, respiratory epithelium.
Anti-GPRC6A antibody APR12254G IHC of human kidney.
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說明書 |
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數量 |
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