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CHRM2 / M2 Antibody (Cytoplasmic Domain)

AMM05764G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
AMM05764G		50 μg / ￥4950

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CHRM2 / M2 Antibody (Cytoplasmic Domain)

品牌	Leading Biology	貨號	AMM05764G
產(chǎn)品分類	Polyclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CHRM2 / M2 antibody (Cytoplasmic Domain).
分子量	52kDa
細胞定位	Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Note=Phosphorylation in response to agonist binding promotes receptor internalization.
宿主	Rabbit
種屬反應性	Human, Mouse, Rabbit, Hamster, Monkey, Pig, Sheep, Bovine, Guinea Pig, Dog
靶點	Human CHRM2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
基因ID	1129
UniProt ID	P08172
功能	The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol.
總結	The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol.
形式	Liquid
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	IHC-P
稀釋方法	IHC-P (4 μg/ml)
別名	Muscarinic acetylcholine receptor M2, CHRM2
圖像	Anti-CHRM2 / M2 antibody IHC of human Skin, Melanoma. Anti-CHRM2 antibody AMM05764G IHC of human brain, neurons and glia. Anti-CHRM2 / M2 antibody IHC of human Brain, Glioblastoma.
說明書	Product Datasheet Protocol
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