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> 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > GCGR / Glucagon Receptor Antibody (N-Terminus)品牌 |
Leading Biology | 貨號 |
AMM04745G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GCGR / Glucagon Receptor antibody (N-Terminus).
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分子量 |
54kDa
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein. Note=Is rapidly internalized after ligand-binding
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點 |
Human Glucagon Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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基因ID |
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UniProt ID |
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功能 |
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
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總結(jié) |
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC-P
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稀釋方法 |
IHC-P (2-5 μg/ml)
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別名 |
Glucagon receptor, GL-R, GCGR
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圖像 |
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說明書 |
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數(shù)量 |
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