LGR6 Antibody (Internal)

APR17189G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR17189G		50 μg / ￥4950

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LGR6 Antibody (Internal)

品牌	Leading Biology	貨號(hào)	APR17189G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LGR6 antibody (Internal).
分子量	104kDa
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein
宿主	Rabbit
種屬反應(yīng)性	Human
靶點(diǎn)	Human LGR6. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
基因ID	59352
UniProt ID	Q9HBX8
功能	Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
總結(jié)	Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	IHC-P
稀釋方法	IHC-P (10 μg/ml)
別名	Leucine-rich repeat-containing G-protein coupled receptor 6, LGR6
圖像	Anti-LGR6 antibody APR17189G IHC of human neutrophils. Anti-LGR6 antibody APR17189G IHC of human spleen.
說(shuō)明書(shū)	Product Datasheet Protocol
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