IRS-1 Antibody (S636)

APR08034G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
APR08034G		0.1 mg / ￥4950

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IRS-1 Antibody (S636)

品牌	Leading Biology	貨號(hào)	APR08034G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IRS-1 antibody (S636).
分子量	131591 Da
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點(diǎn)	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
亞型	Rabbit IgG
基因ID	3667
UniProt ID	P35568
功能	May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).
總結(jié)	This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.
形式	affinity Purified IgG, in PBS, 0.02% sodium azide and 50% glycerol.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, IF
稀釋方法	WB~~1:500~1:1000 IHC~~1:50~1:100 IF~~1:100~200
別名	Insulin receptor substrate 1, IRS-1, IRS1
圖像	Western blot analysis of extracts from 293 cells treated with insulin(100nM, 30min) or PMA (0.2?M, 15min) using IRS-1 Antibody (S636) ( APR08034G, Lane 1, 2 and 3) and Phospho-IRS-1-S636 Antibody ( AE1018c, Lane 4, 5 and 6). Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using IRS-1 Antibody (S636) ( APR08034G). Immunofluorescence staining of methanol-fixed HeLa cells using IRS-1 Antibody (S636) ( APR08034G,Red).
說(shuō)明書(shū)	Product Datasheet Protocol
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