品牌 |
Leading Biology |
貨號 |
APR16077G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GATA1 antibody (S142).
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分子量 |
42751 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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亞型 |
Rabbit IgG
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通用名 |
ERYF1, GF1
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基因ID |
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UniProt ID |
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功能 |
Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.
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總結(jié) |
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.
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形式 |
affinity Purified IgG, in PBS, 0.02% sodium azide and 50% glycerol.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, IF
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稀釋方法 |
WB~~1:500~1:1000
IHC~~1:50~1:100
IF~~1:100~200
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別名 |
Erythroid transcription factor, Eryf1, GATA-binding factor 1, GATA-1, GF-1, NF-E1 DNA-binding protein, GATA1, ERYF1, GF1
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圖像 |
Western blot analysis of extracts from K562 cells using
GATA1 Antibody (S142) ( APR16077G).
Immunohistochemical analysis of paraffin-embedded
human breast carcinoma tissue using GATA1 Antibody (S142) ( APR16077G).
Immunofluorescence staining of methanol-fixed HeLa cells using GATA1 Antibody (S142) ( APR16077G,Red).
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說明書 |
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數(shù)量 |
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