Phospho-ADD1-S726 Antibody

APR12826G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR12826G		0.1 mg / ￥4950

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安諾倫（北京）生物科技有限公司

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Phospho-ADD1-S726 Antibody

品牌	Leading Biology	貨號(hào)	APR12826G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-ADD1-S726 antibody.
分子量	80955 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點(diǎn)	The antibody was affinity-purified from rabbit antiserum using epitope-specific phosphopeptide column, and the antibody against non-phosphopeptide was removed using non-phosphopeptide column corresponding to the phosphorylation site.
亞型	Rabbit IgG
通用名	ADDA
基因ID	118
UniProt ID	P35611
功能	Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.
總結(jié)	Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
形式	affinity Purified IgG, in PBS, 0.02% sodium azide and 50% glycerol.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, IF
稀釋方法	WB~~1:500~1:1000 IHC~~1:50~1:100 IF~~1:100~200
別名	Alpha-adducin, Erythrocyte adducin subunit alpha, ADD1, ADDA
圖像	Western blot analysis of extract from HT-29 cells untreated ortreated with Doxorubicin (1mM, 30min), using ADD1 Antibody (S726) ( Lane 1 and 2) and Phospho-ADD1-S726 Antibody ( APR12826G, Lane 3 and 4). Immunohistochemical analysis of paraffin- embedded human lung carcinoma tissue using Phospho-ADD1-S726 Antibody ( APR12826G). Immunofluorescence staining of methanol-fixed HeLa cells using Phospho-ADD1-S726 Antibody ( APR12826G, Red).
說(shuō)明書(shū)	Product Datasheet Protocol
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