全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR14006G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality YWHAZ antibody (S58).
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分子量 |
27745 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Melanosome. Note=Located to stage I to stage IV melanosomes
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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亞型 |
Rabbit IgG
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基因ID |
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UniProt ID |
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功能 |
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
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總結(jié) |
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.
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形式 |
affinity Purified IgG, in PBS, 0.02% sodium azide and 50% glycerol.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC
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稀釋方法 |
WB~~1:500~1:1000
IHC~~1:50~1:100
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別名 |
14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1, YWHAZ
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圖像 |
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說明書 |
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數(shù)量 |
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