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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > SMAD1 Antibody (Center)

SMAD1 Antibody (Center)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR17871G 100 μl / ¥4950

SMAD1 Antibody (Center)

品牌

Leading Biology

貨號(hào)

APR17871G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SMAD1 antibody (Center).

分子量

H=52;M=52;Rat=53 KDa

細(xì)胞定位

Antigen Cellular Localization: Cytoplasm. Nucleus. Note=Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4. Co-localizes with LEMD3 at the nucleus inner membrane

宿主

Rabbit

種屬反應(yīng)性

Human, Rat

免疫原

163-196 aa

靶點(diǎn)

This SMAD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 163-196 amino acids from the Central region of human SMAD1.

通用名

BSP1, MADH1, MADR1

基因ID

UniProt ID

功能

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.

總結(jié)

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, IF

稀釋方法

WB~~1:1000 IHC-P~~1:25 IF~~1:25

別名

Mothers against decapentaplegic homolog 1, MAD homolog 1, Mothers against DPP homolog 1, JV4-1, Mad-related protein 1, SMAD family member 1, SMAD 1, Smad1, hSMAD1, Transforming growth factor-beta-signaling protein 1, BSP-1, SMAD1, BSP1, MADH1, MADR1

圖像

Western blot analysis of lysates from Hela,HepG2,HT-1080, mouse C2C12 cell line and rat liver tissue lysate (from left to right), using SMAD1 Antibody (Center)(Cat. APR17871G). APR17871G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.

Immunohistochemical analysis of paraffin-embedded H. heart section using SMAD1 Antibody (Center)( APR17871G). APR17871G was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

Immunohistochemical analysis of paraffin-embedded H. skeletal muscle section using SMAD1 Antibody (Center)( APR17871G). APR17871G was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

說明書

數(shù)量

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