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> 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Goat Anti-ABCG2 / BCRP Antibody (internal region)品牌 |
Leading Biology | 貨號(hào) |
AMM04858G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-ABCG2 / BCRP antibody (internal region).
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分子量 |
72314 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein
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宿主 |
Goat
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種屬反應(yīng)性 |
Human
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通用名 |
ABCP, BCRP, BCRP1, MXR
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基因ID |
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UniProt ID |
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功能 |
High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. Implicated in the efflux of numerous drugs and xenobiotics: mitoxantrone, the photosensitizer pheophorbide, camptothecin, methotrexate, azidothymidine (AZT), and the anthracyclines daunorubicin and doxorubicin.
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形式 |
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.Aliquot and store at -20°C. Minimize freezing and thawing.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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別名 |
ABCG2; ATP-binding cassette, sub-family G (WHITE), member 2; ABC15; ABCP; BCRP; BCRP1; BMDP; CD338; CDw338; EST157481; GOUT1; MRX; MXR; MXR1; UAQTL1; ABC transporter; ATP-binding cassette sub-family G member 2; ATP-binding cassette transporter G2; breast
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圖像 |
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說(shuō)明書(shū) |
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數(shù)量 |
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