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Goat Anti-PGC1A Antibody (internal region)品牌 |
Leading Biology | 貨號(hào) |
AMM05085G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-PGC1A antibody (internal region).
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分子量 |
91027 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Isoform 1: Nucleus. Nucleus, PML body. Isoform B4-8a: Cytoplasm. Nucleus. Isoform 9: Nucleus
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宿主 |
Goat
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種屬反應(yīng)性 |
Human
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通用名 |
LEM6, PGC1, PGC1A, PPARGC1
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基因ID |
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UniProt ID |
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功能 |
Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner. Also involved in the integration of the circadian rhythms and energy metabolism. Required for oscillatory expression of clock genes, such as ARNTL/BMAL1 and NR1D1, through the coactivation of RORA and RORC, and metabolic genes, such as PDK4 and PEPCK.
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形式 |
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.Aliquot and store at -20°C. Minimize freezing and thawing.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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別名 |
PGC1A; PPARGC1A; peroxisome proliferator-activated receptor gamma, coactivator 1 alpha; LEM6; PGC-1(alpha); PGC-1v; PGC1; PPARGC1; PPAR gamma coactivator variant form; PPAR gamma coactivator-1; ligand effect modulator-6; peroxisome proliferative activated receptor; gamma, coactivator 1; peroxisome proliferative activated receptor, gamma, coactivator 1, alpha
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圖像 |
AMM05085G (0.1 μg/ml) staining of Human Skeletal Muscle lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. |
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說明書 |
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數(shù)量 |
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