全部產品分類
品牌 |
Leading Biology | 貨號 |
AMM04765G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GGT1 (aa180-193) antibody (internal region).
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分子量 |
61410 Da
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type II membrane protein
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宿主 |
Goat
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種屬反應性 |
Human
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亞型 |
IgG
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通用名 |
GGT
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基因ID |
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UniProt ID |
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功能 |
Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide, cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.
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總結 |
Reported variants represent identical protein: NP_038347.2, NP_001027536.1, NP_001027537.1, NP_005256.2.
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形式 |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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別名 |
Gamma-glutamyltranspeptidase 1, GGT 1, 2.3.2.2, Gamma-glutamyltransferase 1, Glutathione hydrolase 1, 3.4.19.13, Leukotriene-C4 hydrolase, 3.4.19.14, CD224, Gamma-glutamyltranspeptidase 1 heavy chain, Gamma-glutamyltranspeptidase 1 light chain, GGT1, GGT
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圖像 |
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說明書 |
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數量 |
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