品牌 |
Leading Biology |
貨號(hào) |
APR09935G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality sialin / SLC17A5 (aa85-99) antibody (internal region).
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分子量 |
54640 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane Lysosome membrane; Multi-pass membrane protein
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宿主 |
Goat
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種屬反應(yīng)性 |
Human
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亞型 |
IgG
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基因ID |
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UniProt ID |
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功能 |
Transports glucuronic acid and free sialic acid out of the lysosome after it is cleaved from sialoglycoconjugates undergoing degradation, this is required for normal CNS myelination. Mediates aspartate and glutamate membrane potential- dependent uptake into synaptic vesicles and synaptic-like microvesicles. Also functions as an electrogenic 2NO(3)(-)/H(+) cotransporter in the plasma membrane of salivary gland acinar cells, mediating the physiological nitrate efflux, 25% of the circulating nitrate ions is typically removed and secreted in saliva.
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形式 |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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別名 |
Sialin, H(+)/nitrate cotransporter, H(+)/sialic acid cotransporter, AST, Membrane glycoprotein HP59, Solute carrier family 17 member 5, Vesicular H(+)/Aspartate-glutamate cotransporter, SLC17A5
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圖像 |
APR09935G (1 μg/ml) staining of Human Placenta lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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說(shuō)明書(shū) |
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數(shù)量 |
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