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當(dāng)前位置：首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Fibrillarin / FBL Antibody (internal region)

Fibrillarin / FBL Antibody (internal region)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR15958G 0.1 mg / ￥4950

Fibrillarin / FBL Antibody (internal region)

品牌

 Leading Biology

貨號(hào)

 APR15958G

產(chǎn)品分類

 Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Fibrillarin / FBL antibody (internal region).

分子量
33784 Da

細(xì)胞定位
Antigen Cellular Localization: Nucleus, nucleolus Note=Fibrillar region of the nucleolus

宿主
Goat

種屬反應(yīng)性
Human

亞型
IgG

通用名
FIB1, FLRN

基因ID

UniProt ID

功能
S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ104me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (PubMed:24352239).

形式
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

儲(chǔ)存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用
WB, E

別名
rRNA 2'-O-methyltransferase fibrillarin, 2.1.1.-, 34 kDa nucleolar scleroderma antigen, Histone-glutamine methyltransferase, FBL, FIB1, FLRN

圖像

APR15958G (1 μg/ml) staining of HEK293 lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

說(shuō)明書

數(shù)量

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