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Histamine Receptor H2 (aa309-323) Antibody (internal region)品牌 |
Leading Biology | 貨號 |
APR16641G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Histamine Receptor H2 (aa309-323) antibody (internal region).
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分子量 |
40098 Da
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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宿主 |
Goat
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種屬反應性 |
Human
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亞型 |
IgG
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基因ID |
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UniProt ID |
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功能 |
The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity).
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總結(jié) |
This antibody is expected to recognize both reported isoforms (NP_001124527.1; NP_071640.1).
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形式 |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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別名 |
Histamine H2 receptor, H2R, HH2R, Gastric receptor I, HRH2
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圖像 |
APR16641G (0.1 μg/ml) staining of Duodenum lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. |
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說明書 |
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數(shù)量 |
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