KCNIP3 Antibody (internal region)

AMM06123G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
AMM06123G		0.1 mg / ￥4950

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KCNIP3 Antibody (internal region)

品牌	Leading Biology	貨號	AMM06123G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KCNIP3 antibody (internal region).
分子量	29231 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Cell membrane; Lipid-anchor. Endoplasmic reticulum. Golgi apparatus. Nucleus. Note=Also membrane-bound, associated with the plasma membrane (By similarity). In the presence of PSEN2 associated with the endoplasmic reticulum and Golgi. The sumoylated form is present only in the nucleus.
宿主	Goat
種屬反應(yīng)性	Human
亞型	IgG
通用名	CSEN, DREAM, KCHIP3
基因ID	30818
UniProt ID	Q9Y2W7
功能	Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity). May play a role in the regulation of PSEN2 proteolytic processing and apoptosis. Together with PSEN2 involved in modulation of beta-amyloid formation.
總結(jié)	This antibody is expected to recognize isoform 1 (NP_038462.1) only.
形式	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
別名	Calsenilin, A-type potassium channel modulatory protein 3, DRE-antagonist modulator, DREAM, Kv channel-interacting protein 3, KChIP3, KCNIP3, CSEN, DREAM, KCHIP3
圖像	HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human KCNIP3 with C-terminal MYC tag probed with AMM06123G (1ug/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with AMM06123G (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence.
說明書	Product Datasheet Protocol
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