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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > GM2A (aa 164-175) Antibody (internal region)

GM2A (aa 164-175) Antibody (internal region)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR16168G 0.1 mg / ¥4950

GM2A (aa 164-175) Antibody (internal region)

品牌

Leading Biology

貨號(hào)

APR16168G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GM2A (aa 164-175) antibody (internal region).

分子量

20838 Da

細(xì)胞定位

Antigen Cellular Localization: Lysosome.

宿主

Goat

種屬反應(yīng)性

Human, Rat

亞型

IgG

基因ID

UniProt ID

功能

The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta- hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.

總結(jié)

This antibody is expected to recognize isoform 1 (NP_000396.2) only.

形式

0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

別名

Ganglioside GM2 activator, Cerebroside sulfate activator protein, GM2-AP, Sphingolipid activator protein 3, SAP-3, Ganglioside GM2 activator isoform short, GM2A

圖像

HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human GM2A with DYKDDDDK tag probed with APR16168G (1.0ug/ml) in Lane A and probed with anti- DYKDDDDK Tag (1/30000) in lane C. Mock-transfected HEK293 probed with APR16168G (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence.

APR16168G (0.3 μg/ml) staining of Rat Kidney lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

說明書

數(shù)量

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