MCF2L Antibody (internal region)

APR17333G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR17333G		0.1 mg / ￥4950

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MCF2L Antibody (internal region)

品牌	Leading Biology	貨號(hào)	APR17333G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MCF2L antibody (internal region).
分子量	128109 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side
宿主	Goat
種屬反應(yīng)性	Human
亞型	IgG
通用名	KIAA0362
基因ID	23263
UniProt ID	O15068
功能	Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42.
總結(jié)	This antibody is expected to recognize both reported isoforms (NP_001106203.1; NP_079255.3).
形式	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
別名	Guanine nucleotide exchange factor DBS, DBL's big sister, MCF2-transforming sequence-like protein, MCF2L, KIAA0362
圖像	APR17333G (1 μg/ml) staining of Jurkat (A) and Human Thymus (B) lysates (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
說(shuō)明書	Product Datasheet Protocol
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