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> 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > NFATC2 / NFAT1 Antibody (internal region)品牌 |
Leading Biology | 貨號 |
APR08728G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NFATC2 / NFAT1 antibody (internal region).
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分子量 |
100146 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals The subcellular localization of NFATC plays a key role in the regulation of gene transcription
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宿主 |
Goat
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種屬反應(yīng)性 |
Human
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亞型 |
IgG
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通用名 |
NFAT1, NFATP
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基因ID |
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UniProt ID |
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功能 |
Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway.
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總結(jié) |
This antibody is expected to recognize all three reported isoforms (NP_036472.2; NP_775114.1; NP_001129493.1).
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形式 |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, E
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別名 |
Nuclear factor of activated T-cells, cytoplasmic 2, NF-ATc2, NFATc2, NFAT pre-existing subunit, NF-ATp, T-cell transcription factor NFAT1, NFATC2, NFAT1, NFATP
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圖像 |
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說明書 |
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數(shù)量 |
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