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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > ITM2B Antibody (internal region)

ITM2B Antibody (internal region)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM06029G 0.1 mg / ¥4950

ITM2B Antibody (internal region)

品牌

Leading Biology

貨號(hào)

AMM06029G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ITM2B antibody (internal region).

分子量

30338 Da

細(xì)胞定位

Antigen Cellular Localization: Integral membrane protein 2B: Golgi apparatus membrane; Single-pass type II membrane protein Note=Immature BRI2 (imBRI2) is cleaved by furin in the Golgi into mBRI2 and a Bri23 peptide. mBRI2 is transported to the plasma membrane and Bri23 peptide is secreted Bri23 peptide: Secreted. Note=Detected in the cerebral spinal fluid (CSF)

宿主

Goat

種屬反應(yīng)性

Human

亞型

IgG

通用名

BRI, BRI2

基因ID

UniProt ID

功能

Plays a regulatory role in the processing of the beta- amyloid A4 precursor protein (APP) and acts as an inhibitor of the beta-amyloid peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites. Bri23 peptide prevents aggregation of APP beta-amyloid protein 42 peptide into toxic oligomers.

形式

0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

別名

Integral membrane protein 2B, Immature BRI2, imBRI2, Protein E25B, Transmembrane protein BRI, Bri, BRI2, membrane form, Mature BRI2, mBRI2, BRI2 intracellular domain, BRI2 ICD, BRI2C, soluble form, Bri23 peptide, Bri2-23, ABri23, C-terminal peptide, P23 peptide, ITM2B, BRI, BRI2

圖像

AMM06029G (1 μg/ml) staining of Human Hippocampus lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

說(shuō)明書(shū)

數(shù)量

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