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Cdc42-binding kinase alpha Antibody (N-Term)

APR15361G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR15361G		0.1 mg / ￥4950

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Cdc42-binding kinase alpha Antibody (N-Term)

品牌	Leading Biology	貨號	APR15361G
產品分類	Polyclonal Antibodies	研究領域
產品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Cdc42-binding kinase alpha antibody (N-Term).
分子量	197307 Da
細胞定位	Antigen Cellular Localization: Cytoplasm. Note=Displays a dispersed punctate distribution and concentrates along the cell periphery, especially at the leading edge and cell-cell junction This concentration is PH-domain dependent (By similarity)
宿主	Goat
種屬反應性	Human
亞型	IgG
通用名	KIAA0451
基因ID	8476
UniProt ID	Q5VT25
功能	Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates: PPP1R12A, LIMK1 and LIMK2. May play a role in TFRC-mediated iron uptake.
總結	This antibody is expected to recognise both reported Human isoforms (NP_055641.3 and NP_003598.2).
形式	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	IHC, E
別名	Serine/threonine-protein kinase MRCK alpha, 2.7.11.1, CDC42-binding protein kinase alpha, DMPK-like alpha, Myotonic dystrophy kinase-related CDC42-binding kinase alpha, MRCK alpha, Myotonic dystrophy protein kinase-like alpha, CDC42BPA {ECO:0000312\|EMBL:CAH71336.1}, KIAA0451
圖像	APR15361G (3.8 μg/ml) staining of paraffin embedded Human Cerebellum Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
說明書	Product Datasheet Protocol
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