RANBP8 / IPO8 Antibody (C-Term)

AMM07517G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM07517G		0.1 mg / ￥4950

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RANBP8 / IPO8 Antibody (C-Term)

品牌	Leading Biology	貨號(hào)	AMM07517G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RANBP8 / IPO8 antibody (C-Term).
分子量	119938 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Nucleus
宿主	Goat
種屬反應(yīng)性	Human
亞型	IgG
通用名	RANBP8
基因ID	10526
UniProt ID	O15397
功能	Seems to function in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter- like protein in association with the importin-beta subunit KPNB1. Acting autonomously, is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro mediates the nuclear import of SRP19.
總結(jié)	This antibody is expected to recognise isoform 1 (NP_006381.2) and isoform 2 (NP_001177924.1).
形式	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	IHC, E
別名	Importin-8, Imp8, Ran-binding protein 8, RanBP8, IPO8, RANBP8
圖像	AMM07517G (4 μg/ml) staining of paraffin embedded Human Tonsil. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining. Similar results were obtained after antigen retrieval at pH9.
說(shuō)明書(shū)	Product Datasheet Protocol
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