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全部產(chǎn)品分類(lèi)
品牌 |
Leading Biology | 貨號(hào) |
AMM04927G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-CCAR1 antibody.
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分子量 |
132821 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm, perinuclear region
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宿主 |
Goat
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種屬反應(yīng)性 |
Mouse, Rat
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亞型 |
IgG
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通用名 |
CARP1, DIS
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基因ID |
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UniProt ID |
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功能 |
Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation.
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形式 |
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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別名 |
Cell division cycle and apoptosis regulator protein 1, Cell cycle and apoptosis regulatory protein 1, CARP-1, Death inducer with SAP domain, CCAR1, CARP1, DIS
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圖像 |
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說(shuō)明書(shū) |
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數(shù)量 |
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