品牌 |
Leading Biology |
貨號 |
APR16268G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-DTX3 antibody.
|
分子量 |
37988 Da
|
細胞定位 |
Antigen Cellular Localization:
Cytoplasm.
|
宿主 |
Goat
|
種屬反應(yīng)性 |
Mouse
|
亞型 |
IgG
|
通用名 |
RNF154
|
基因ID |
|
UniProt ID |
|
功能 |
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
|
總結(jié) |
DTX3 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).
|
形式 |
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
|
儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
應(yīng)用 |
WB, E
|
別名 |
Probable E3 ubiquitin-protein ligase DTX3, 6.3.2.-, Protein deltex-3, Deltex3, RING finger protein 154, DTX3, RNF154
|
圖像 |
APR16268G (0.3 μg/ml) staining of NIH3T3 lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
|
說明書 |
|
數(shù)量 |
|