Goat Anti-TSPO / PBR (isoform) Antibody

AMM05148G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM05148G		0.1 mg / ￥4950

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Goat Anti-TSPO / PBR (isoform) Antibody

品牌	Leading Biology	貨號(hào)	AMM05148G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-TSPO / PBR (isoform) antibody.
分子量	18828 Da
細(xì)胞定位	Antigen Cellular Localization: Mitochondrion membrane; Multi-pass membrane protein
宿主	Goat
種屬反應(yīng)性	Human
亞型	IgG
通用名	BZRP, MBR
基因ID	706
UniProt ID	P30536
功能	Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides(PubMed:1847678).
總結(jié)	Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
形式	0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, E
別名	Translocator protein, Mitochondrial benzodiazepine receptor, PKBS, Peripheral-type benzodiazepine receptor, PBR, TSPO, BZRP, MBR
圖像	AMM05148G (0.1 μg/ml) staining of Human Breast Cancer lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. AMM05148G (2.5 μg/ml) staining of paraffin embedded Human Colon. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
說(shuō)明書(shū)	Product Datasheet Protocol
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