品牌 |
Leading Biology | 貨號(hào) |
AMM05137G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-STK39 / SPAK antibody.
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分子量 |
59474 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Nucleus when caspase-cleaved.
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宿主 |
Goat
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種屬反應(yīng)性 |
Human, Mouse, Rat
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亞型 |
IgG
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通用名 |
SPAK
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基因ID |
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UniProt ID |
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功能 |
May act as a mediator of stress-activated signals.
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總結(jié) |
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.
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形式 |
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, E
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別名 |
STE20/SPS1-related proline-alanine-rich protein kinase, Ste-20-related kinase, 2.7.11.1, DCHT, Serine/threonine-protein kinase 39, STK39, SPAK
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圖像 |
AMM05137G (0.5 μg/ml) staining of Jurkat lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. AMM05137G (3.8 μg/ml) staining of paraffin embedded Human Cerebral Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. |
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說(shuō)明書(shū) |
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數(shù)量 |
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