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> 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Goat Anti-Phosphodiesterase 4B Antibody品牌 |
Leading Biology | 貨號(hào) |
APR16360G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-Phosphodiesterase 4B antibody.
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分子量 |
83343 Da
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宿主 |
Goat
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種屬反應(yīng)性 |
Mouse
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亞型 |
IgG
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通用名 |
DPDE4
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基因ID |
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UniProt ID |
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功能 |
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.
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總結(jié) |
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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形式 |
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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別名 |
cAMP-specific 3', 5'-cyclic phosphodiesterase 4B, 3.1.4.53, DPDE4, PDE32, PDE4B, DPDE4
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圖像 |
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說(shuō)明書(shū) |
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數(shù)量 |
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