全部產品分類
品牌 |
Leading Biology | 貨號 |
AMM05065G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-OSBP antibody.
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分子量 |
89421 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Note=When bound to oxysterols, translocates to the periphery of Golgi membranes
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宿主 |
Goat
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種屬反應性 |
Human
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亞型 |
IgG
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通用名 |
OSBP1
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基因ID |
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UniProt ID |
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功能 |
Binds cholesterol and a range of oxysterols. Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylate ERK1/2, whereas 25- hydroxycholesterol causes its disassembly. Regulates cholesterol efflux by decreasing ABCA1 stability.
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總結 |
Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase
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形式 |
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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別名 |
Oxysterol-binding protein 1, OSBP, OSBP1
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圖像 |
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說明書 |
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數(shù)量 |
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