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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Goat Anti-OCT4 / POU5F1 Antibody

Goat Anti-OCT4 / POU5F1 Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR16334G 0.1 mg / ¥4950

Goat Anti-OCT4 / POU5F1 Antibody

品牌

Leading Biology

貨號(hào)

APR16334G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-OCT4 / POU5F1 antibody.

分子量

38571 Da

細(xì)胞定位

Antigen Cellular Localization: Cytoplasm. Nucleus. Note=Expressed in a diffuse and slightly punctuate pattern

宿主

Goat

種屬反應(yīng)性

Human

亞型

IgG

通用名

OCT3, OCT4, OTF3

基因ID

UniProt ID

功能

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.

總結(jié)

This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

形式

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

別名

POU domain, class 5, transcription factor 1, Octamer-binding protein 3, Oct-3, Octamer-binding protein 4, Oct-4, Octamer-binding transcription factor 3, OTF-3, POU5F1, OCT3, OCT4, OTF3

圖像

APR16334G (2 μg/ml) staining of Human Placenta lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

說明書

數(shù)量

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