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Polyclonal Antibodies >
Goat Anti-MUNC18 / STXBP1 (isoform a) Antibody品牌 |
Leading Biology | 貨號(hào) |
AMM05043G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-MUNC18 / STXBP1 (isoform a) antibody.
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分子量 |
67569 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein
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宿主 |
Goat
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種屬反應(yīng)性 |
Human, Mouse
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亞型 |
IgG
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通用名 |
UNC18A
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基因ID |
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UniProt ID |
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功能 |
May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
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總結(jié) |
This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described.
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形式 |
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, E
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別名 |
Syntaxin-binding protein 1, MUNC18-1, N-Sec1, Protein unc-18 homolog 1, Unc18-1, Protein unc-18 homolog A, Unc-18A, p67, STXBP1, UNC18A
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圖像 |
AMM05043G (0.1 μg/ml) staining of Human Brain lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. AMM05043G (5 μg/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. |
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說(shuō)明書(shū) |
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數(shù)量 |
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