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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Goat Anti-HMOX2 Antibody

Goat Anti-HMOX2 Antibody

貨號 貨期 規(guī)格 / 價格 詢價
AMM05013G 0.1 mg / ¥4950

Goat Anti-HMOX2 Antibody

品牌

Leading Biology

貨號

AMM05013G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-HMOX2 antibody.

分子量

36033 Da

細胞定位

Antigen Cellular Localization: Microsome. Endoplasmic reticulum.

宿主

Goat

種屬反應(yīng)性

Human

亞型

IgG

通用名

HO2

基因ID

UniProt ID

功能

Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.

總結(jié)

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Alternative splice variants encoding the same protein have been identified at this locus.

形式

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC, E

別名

Heme oxygenase 2, HO-2, 1.14.99.3, HMOX2, HO2

圖像

AMM05013G (2 μg/ml) staining of paraffin embedded Human Pancreas: cancer (left), adjacent to cancer (right). Steamed antigen retrieval with citrate buffer pH 6, Alexa594-staining.

AMM05013G (0.3 μg/ml) staining of K562 cell lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

說明書

數(shù)量

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