品牌 |
Leading Biology | 貨號(hào) |
APR16277G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-EXOC7 antibody.
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分子量 |
83382 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein Note=Translocates, as a preformed complex with SEC6 and SEC8, to the plasma membrane in response to insulin through the activation of ARHQ.
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宿主 |
Goat
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種屬反應(yīng)性 |
Human
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亞型 |
IgG
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通用名 |
EXO70, KIAA1067
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基因ID |
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UniProt ID |
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功能 |
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion (By similarity).
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總結(jié) |
EXOC7 is a component of the exocyst, which is an evolutionarily conserved octameric protein complex essential for exocytosis. The exocyst targets secretory vesicles at specific domains of the plasma membrane for cell surface expansion and protein secretion (Zuo et al., 2006 [PubMed 17086175]).
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形式 |
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, E
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別名 |
Exocyst complex component 7, Exocyst complex component Exo70, EXOC7, EXO70, KIAA1067
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圖像 |
APR16277G (0.5 μg/ml) staining of Human Lung lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. APR16277G (0.5 μg/ml) staining of paraffin embedded Human Pancreas. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. |
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說(shuō)明書(shū) |
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數(shù)量 |
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