品牌 |
Leading Biology | 貨號 |
APR12090G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-DYX1C1 / EKN1 antibody.
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分子量 |
48527 Da
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細胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm.
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宿主 |
Goat
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種屬反應性 |
Human
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亞型 |
IgG
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通用名 |
EKN1
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基因ID |
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UniProt ID |
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功能 |
Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. Axonemal dynein assembly factor required for ciliary motility.
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總結 |
This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternate splicing results in multiple transcript variants.
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形式 |
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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別名 |
Dyslexia susceptibility 1 candidate gene 1 protein, DYX1C1, EKN1
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圖像 |
APR12090G (0.5 μg/ml) staining of Human Brain (Frontal Cortex) lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. |
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說明書 |
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數(shù)量 |
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