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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Goat Anti-Alsin / ALS2 Antibody

Goat Anti-Alsin / ALS2 Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR12066G 0.1 mg / ¥4950

Goat Anti-Alsin / ALS2 Antibody

品牌

Leading Biology

貨號(hào)

APR12066G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-Alsin / ALS2 antibody.

分子量

183634 Da

宿主

Goat

種屬反應(yīng)性

Human

亞型

IgG

通用名

ALS2CR6, KIAA1563

基因ID

UniProt ID

功能

May act as a GTPase regulator. Controls survival and growth of spinal motoneurons (By similarity).

總結(jié)

The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.

形式

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

IHC, E

別名

Alsin, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein, Amyotrophic lateral sclerosis 2 protein, ALS2, ALS2CR6, KIAA1563

圖像

APR12066G (3.8 μg/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

說(shuō)明書(shū)

數(shù)量

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