Goat Anti-ABCB9 / TAPL Antibody

APR16196G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR16196G		0.1 mg / ￥4950

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安諾倫（北京）生物科技有限公司

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Goat Anti-ABCB9 / TAPL Antibody

品牌	Leading Biology	貨號(hào)	APR16196G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-ABCB9 / TAPL antibody.
分子量	84475 Da
細(xì)胞定位	Antigen Cellular Localization: Lysosome membrane; Multi- pass membrane protein {ECO:0000255\|PROSITE-ProRule:PRU00441, ECO:0000269\|PubMed:10748049, ECO:0000269\|PubMed:15577206, ECO:0000269\|PubMed:17897319, ECO:0000269\|PubMed:17977821, ECO:0000269\|PubMed:18175933, ECO:0000269\|PubMed:18952056, ECO:0000269\|PubMed:20377823, ECO:0000269\|PubMed:21212514} Note=May be located in membrane rafts
宿主	Goat
種屬反應(yīng)性	Human
亞型	IgG
通用名	KIAA1520
基因ID	23457
UniProt ID	Q9NP78
功能	ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored.
總結(jié)	The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, this protein may play a role in lysosomes. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specifications.
形式	0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	IHC, E
別名	ATP-binding cassette sub-family B member 9, ATP-binding cassette transporter 9, ABC transporter 9 protein, hABCB9, TAP-like protein, TAPL, ABCB9, KIAA1520
圖像	APR16196G (3.8 μg/ml) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
說明書	Product Datasheet Protocol
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