全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR10537G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Transglutaminase-2 antibody.
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分子量 |
77329 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點 |
Transglutaminase-2
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亞型 |
Rabbit IgG
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基因ID |
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UniProt ID |
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功能 |
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
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總結(jié) |
Tissue transglutaminase, a 78-kDa calcium dependent enzyme (EC 2.3.2.13), is found both in the intracellular and the extracellular spaces of various types of tissues. TG2 crosslinks proteins between the ε-amino group of a lysine residue and the γ-carboxamide group of glutamine residue, creating an inter- or intramolecular bond that is highly resistant to proteolysis (protein degradation). TG2 also possesses deamidation, GTP-binding/hydrolyzing, and isopeptidase activities. Intracellular TG2 is thought to play an important role in apoptosis, while extracellular TG2 has been linked to cell adhesion, ECM stabilization, wound healing, receptor signaling, cellular proliferation, and cellular motility.
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形式 |
100 μg (0.5 mg/ml) of antibody in PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin?, and 50 % glycerol.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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別名 |
TGM2, Protein-glutamine gamma-glutamyltransferase 2, Tissue transglutaminase, TG, TGC, TGase C, Transglutaminase H, TGase H, TGase-2
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圖像 |
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說明書 |
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數(shù)量 |
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