品牌 |
Leading Biology |
貨號(hào) |
APR08003G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Insulin antibody.
|
分子量 |
11981 Da
|
細(xì)胞定位 |
Antigen Cellular Localization:
Secreted.
|
宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
|
靶點(diǎn) |
Insulin
|
亞型 |
Rabbit IgG
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基因ID |
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UniProt ID |
|
功能 |
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
|
總結(jié) |
Insulin is important in stimulating the uptake of glucose from blood in the skeletal muscle and adipose tissue. It is secrered by pancreatic β cells thro μgh a glucose sensing pathway. Insulin also increases cell permeability to monosaccharides, amino acids and fatty acids. Insulin is first formed as a precursor molecule, preproinsulin which is then processed into proinsulin and finally to the mature insulin hormone. A mature form of insulin has an A chain and a B chain that are connnected by two dilsufide bonds. Defects in insulin are the cause of type-II diabetes mellitus.
|
形式 |
Liquid
|
儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
應(yīng)用 |
WB
|
別名 |
Insulin A chain, Insulin B chain, Proinsulin
|
圖像 |
Western blot analysis using recombinant human Insulin.
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說(shuō)明書 |
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數(shù)量 |
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