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> 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > TFAM (Transcription Factor A, mitochondrial) Antibody品牌 |
Leading Biology | 貨號 |
APR10396G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TFAM (Transcription Factor A, mitochondrial) antibody.
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分子量 |
24 KDa
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
Native recombinant mouse TFAM protein with c-terminal 6-his tag.
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基因ID |
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UniProt ID |
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總結(jié) |
Mitochondrial Transcription Factor A (TFAM) is a key activator of mitochondrial (mt) DNA transcription as well as a participant in mitochondrial genome replication. mtDNA is highly susceptible to oxidative stress leading to mitochondrial dysfunction. Overexpression of TFAM has been implicated in the amelioration of age dependent impairment of brain functions through the prevention of oxidative stress and mitochondrial dysfunction in microglia (Hayashi et al., 2008). More recently, TFAM overexpression has been shown to potentially reduce oxidative stress in motor neurons and delay onset of amyotrophic lateral sclerosis (ALS) in ALS model mice (Morimoto et al., 2012).
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形式 |
serum
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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稀釋方法 |
WB~~ 1:2000
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別名 |
Transcription factor A, mitochondrial, mtTFA, Testis-specific high mobility group protein, TS-HMG, Tfam, Hmgts
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圖像 |
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說明書 |
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數(shù)量 |
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