全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM06519G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Myelin Basic Protein (MBP) antibody.
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分子量 |
18/22 KDa
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宿主 |
Chicken
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種屬反應(yīng)性 |
Bovine, Human, Mouse, Rat
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靶點 |
Three peptide sequences conserved in higher vertebrate MBP proteins.
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基因ID |
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UniProt ID |
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總結(jié) |
Myelin Basic Protein (MBP) is one of the major proteins of the myelin sheath surrounding axons in the nervous system. Since it is of relatively low molecular weight and high abundance the protein sequence was determined from purified protein over 30 years ago (Eylar et al., 1971). The protein is made by oligodendrocytes in the central nervous system, so antibodies to MBP are good markers of this cell type. However, transcripts from the same gene are also expressed in certain hematopoetic lineage cells (Marty et al., 2002). In the central nervous system there are there different forms of the protein made by alternate transcription from a single gene, which have molecular weights of 21.5, 18.5, and 17.2 kDa. Since the two lower molecular weight forms are very close in molecular size, MBP antibodies typically show two bands on Western blots, one at about 22kDa and another at about 18kDa.
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形式 |
Total IgY fraction.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IF
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稀釋方法 |
WB~~ 1:5000
IF~~ 1:500
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別名 |
Myelin basic protein, MBP, Mbp
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圖像 |
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說明書 |
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數(shù)量 |
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